abstract：:Trypanosoma cruzi is the causative agent of Chagas disease, a zoonosis involving domestic and sylvatic mammalian reservoirs. Since scarce information has been published about the susceptibility of T. cruzi lineages to other triatomine species besides Triatoma infestans, we evaluate the susceptibility of T. infestans a...

journal_title：Acta tropica

authors： Campos R,Acuña-Retamar M,Botto-Mahan C,Ortiz S,Cattan PE,Solari A

更新日期：2007-10-01 00:00:00

abstract：:As in the countries edging the Mediterranean basin, Leishmania infantum zymodeme MON-1 is the main causative agent of visceral leishmaniasis in Morocco, where visceral leishmaniasis is most active in the North-Eastern slopes of the Rif mountains. The dog was confirmed to be the main reservoir of L. infantum MON-1, whi...

journal_title：Acta tropica

authors： Haralambous C,Dakkak A,Pratlong F,Dedet JP,Soteriadou K

更新日期：2007-07-01 00:00:00

abstract：:Access to low-cost, effective diagnosis for leptospirosis is urgently needed in developing countries. The EIE-IgM-Leptospirose, a kit produced for public health laboratories in Brazil, was shown to have a sensitivity of 76% (77 of 102 patients) and 100% (102 of 102 patients) during acute and convalescent-phase leptosp...

journal_title：Acta tropica

authors： McBride AJ,Pereira FA,da Silva ED,de Matos RB,da Silva ED,Ferreira AG,Reis MG,Ko AI

更新日期：2007-06-01 00:00:00

abstract：:In this study, Aphanius chantrei's behaviour of feeding on mosquito larvae has been determined under experimental conditions. In groups that have different sizes (first group 27 mm; second group 40 mm; third group 47 mm), larvae consumption has increased with length and weight. During daytime, average larvae consumpti...

journal_title：Acta tropica

authors： Yildirim O,Karacuha A

更新日期：2007-06-01 00:00:00

abstract：:The role of Anopheles funestus group in malaria transmission was investigated in Bagamoyo coastal Tanzania, in the process of characterizing the area as a malaria vaccine testing site. Mosquitoes were sampled inside houses and multiplex PCR was used to identify 649 specimens. The following species were found: A. funes...

journal_title：Acta tropica

authors： Temu EA,Minjas JN,Tuno N,Kawada H,Takagi M

更新日期：2007-05-01 00:00:00

abstract：:Plasma levels of three soluble inducible adhesion molecules, namely: intercellular adhesion molecule-1 (sICAM-1), vascular cell adhesion molecule-1 (sVCAM-1) and endothelial leucocyte adhesion molecule-1 (sELAM-1) or sE-selectin and the pro-inflammatory cytokine, tumour necrosis factor-alpha (TNF-alpha) were measured ...

journal_title：Acta tropica

authors： Tchinda VH,Tadem AD,Tako EA,Tene G,Fogako J,Nyonglema P,Sama G,Zhou A,Leke RG

更新日期：2007-04-01 00:00:00

abstract：:The present paper reports for the first time the capture of wild Triatoma brasiliensis and Triatoma pseudomaculata by means of light traps in Brazil. We tested commercially available lighting devices powered by batteries to attract the bugs to a white piece of cloth in the field. Two main findings showed to be signifi...

journal_title：Acta tropica

authors： Carbajal de la Fuente AL,Minoli SA,Lopes CM,Noireau F,Lazzari CR,Lorenzo MG

更新日期：2007-02-01 00:00:00

abstract：:A cross-sectional sero-epidemiological study was conducted to determine the prevalence of dengue in Trinidad. Two commercial rapid test kits, PanBio Dengue Duo IgM and IgG Rapid Strip Test and the Bio-Check Plus Dengue G/M Cassette Test (Brittney) were used. The immunosorbent assay (ELISA) (FOCUS Technologies, Califor...

journal_title：Acta tropica

authors： Campbell CA,George A,Salas RA,Williams SA,Doon R,Chadee DD

更新日期：2007-02-01 00:00:00

abstract：BACKGROUND:Existing data on human African trypanosomiasis (HAT) due to Trypanosoma brucei gambiense among children are limited. Here, we described the demographic, clinical, diagnostic, treatment and outcome characteristics of HAT in pre-school children from Kajo-Keji County, South Sudan in comparison with older patien...

journal_title：Acta tropica

authors： Eperon G,Schmid C,Loutan L,Chappuis F

更新日期：2007-01-01 00:00:00

abstract：:The drugs currently available for Chagas'disease treatment are unsatisfactory due to limited efficacy and toxic side effects, making the search for more specific pharmacological agents a priority. The components of the Trypanosoma cruzi trypanothione-dependent antioxidant system have been pointed out as potential chem...

journal_title：Acta tropica

authors： Mielniczki-Pereira AA,Chiavegatto CM,López JA,Colli W,Alves MJ,Gadelha FR

更新日期：2007-01-01 00:00:00

abstract：:Azithromycin, an azalide analog of erythromycin was assayed for its in vitro activity against multidrug-resistant Plasmodium falciparum K1 strain by measuring the 3H-hypoxanthine incorporation. Azithromycin caused inhibitory effects on the parasite growth with IC50 and IC90 values of 8.4+/-1.2 microM and 26.0+/-0.9 mi...

journal_title：Acta tropica

authors： Nakornchai S,Konthiang P

更新日期：2006-12-01 00:00:00

abstract：:Leptospirosis is a globally distributed zoonosis of major public health importance and is associated with severe disease manifestations such as acute renal failure and pulmonary haemorrhage syndrome. However, the extent to which the pathogenesis of leptospirosis mimics sepsis caused by Gram-negative bacteria remains u...

journal_title：Acta tropica

authors： Maciel EA,Athanazio DA,Reis EA,Cunha FQ,Queiroz A,Almeida D,McBride AJ,Ko AI,Reis MG

更新日期：2006-12-01 00:00:00

abstract：:Piperazine (diethylenediamine) is an anthelmintic widely used against animal and bird ascariasis. In this study, we show that treatment with piperazine blocks Ascaris suum larval moulting and development processes and affects larval proteome expression profiles. A. suum lung-stage L3 (LL3) obtained from an infected ra...

journal_title：Acta tropica

authors： Islam MK,Miyoshi T,Yamada M,Alim MA,Huang X,Motobu M,Tsuji N

更新日期：2006-10-01 00:00:00

abstract：:Wuchereria bancrofti, a nematode parasite causing human lymphatic filariasis is widely distributed in India. The phylogeography of this parasite was studied by constructing RAPD profiles of parasite populations collected from 71 microfilaria carriers residing in different geoclimatic regions of India. The analysis sho...

journal_title：Acta tropica

authors： Thangadurai R,Hoti SL,Kumar NP,Das PK

更新日期：2006-07-01 00:00:00

abstract：:Fasciola gigantica cathepsin-L cysteine proteinase and recombinant cathepsin L 1-D were assessed for their potential in the immuno-diagnosis of F. gigantica infection in buffaloes. A diagnostic ELISA, based on these two antigens, was developed to detect antibodies against F. gigantica in water buffaloes. Sensitivity o...

journal_title：Acta tropica

authors： Raina OK,Yadav SC,Sriveny D,Gupta SC

更新日期：2006-05-01 00:00:00

abstract：:In this work the effect of a novel compound, 5-epi-icetexone (ICTX) obtained from Salvia gilliessi Benth. (Labiatae), is studied on cultured epimastigotes of Trypanosoma cruzi (Tulahuen). It was found that the compound exerts an antiproliferative effect on the parasites at concentrations between 2.8 and 4.2 microM, an...

journal_title：Acta tropica

authors： Sanchez AM,Jimenez-Ortiz V,Sartor T,Tonn CE,García EE,Nieto M,Burgos MH,Sosa MA

更新日期：2006-05-01 00:00:00

abstract：:The polyamines, spermine and spermidine--organic polycations that are absolutely required for eukaryotic cell growth--are shown here to function in Trypanosoma cruzi epimastigotes, as protectors of membrane lipoperoxidation by reactive oxygen species generated either by H2O2/Fe2+ or nifurtimox. In vitro, spermine and ...

journal_title：Acta tropica

authors： Hernández SM,Sánchez MS,de Tarlovsky MN

更新日期：2006-04-01 00:00:00

abstract：OBJECTIVES:A representative sample of 5722 pre-school children living in rural and urban areas of the Congo was examined between July and September 1999 for assessing Vitamin A deficiency. METHODS:Using a randomized two-level cluster sampling method, 190 clusters of 30 children aged from 6 months to 6 years were selec...

journal_title：Acta tropica

authors： Samba C,Tchibindat F,Houze P,Gourmel B,Malvy D

更新日期：2006-03-01 00:00:00

abstract：:Parenteral quinine is the most frequently used first line treatment for severe Plasmodium falciparum malaria in the developed world. Quinine is known to have a number of toxic side effects including cardiotoxicity, ototoxicity and ocular toxicity. Many therefore advocate routine monitoring of quinine levels for patien...

journal_title：Acta tropica

authors： Flanagan KL,Buckley-Sharp M,Doherty T,Whitty CJ

更新日期：2006-02-01 00:00:00

abstract：:In the present study for the first time an alternative definitive host model has been established for the complete development of Echinococcus granulosus in Meriones unguiculatus (Mongolian gerbils) up to shelled eggs production, as happened in the natural host. Animals treated with methylprednisolone acetate were ora...

journal_title：Acta tropica

authors： Conchedda M,Gabriele F,Bortoletti G

更新日期：2006-02-01 00:00:00

abstract：:Several studies have reported on similar in vitro cellular responses to different malaria-antigen preparations in both malaria-primed and un-primed donors. Whether intact live parasites can exert a distinct type of response in either of the two groups is not well known. In this study, we developed a simple three-step ...

journal_title：Acta tropica

authors： Farouk SE,Shen J,Tangteerawatana P,Bolad A,Berzins K,Troye-Blomberg M

更新日期：2006-01-01 00:00:00

abstract：:A surveillance system has been put in place in the Zhejiang province since achieving there the criteria for transmission interruption of schistosomiasis japonica. Suspected patients and special high-risk groups (e.g. the so called 'floating population' and children under 14 years of age) are screened for Schistosoma j...

journal_title：Acta tropica

authors： Wu WL,Wang JR,Wen LY,Huang YY,Xu XF,Yu WM

更新日期：2005-11-01 00:00:00

abstract：:As part of a study to assess zoonotic milk-borne health risks, seasonal survey data and unpasteurized milk samples were collected between January 1999 and February 2000 from randomly selected informal milk market agents (220 and 236 samples in the dry and wet seasons, respectively) and from households purchasing raw m...

journal_title：Acta tropica

authors： Arimi SM,Koroti E,Kang'ethe EK,Omore AO,McDermott JJ

更新日期：2005-10-01 00:00:00

abstract：:Anopheles minimus, an important malaria vector of South East Asia, has reappeared in the Singhbum hills, East-Central India where deforestation and DDT residual spraying had reportedly eliminated it during the Malaria Eradication Programme. The species reported has been identified as sibling species A of the An. minim...

journal_title：Acta tropica

authors： Jambulingam P,Sahu SS,Manonmani A

更新日期：2005-10-01 00:00:00

abstract：:The promise of new interventions against malaria and other infectious diseases of global health importance derived from pathogen genomic sequence data may only be realized through the coordinated effort of genomic and post-genomics scientists, vaccine and drug developers along with lab- and field-based investigators. ...

journal_title：Acta tropica

authors： Carucci DJ

更新日期：2005-09-01 00:00:00

abstract：:Visceral leishmaniasis is a life-threatening human disease commonly known as kala-azar. Leishmania donovani is the causative agent of this parasitic disease transmitted by the sand fly vector to infect hosts. Triphenyl tin salicylanilide thiosemicarbazone [Ph(3)Sn(OSal.TSCZH)] (TTST) which is an organometallic complex...

journal_title：Acta tropica

authors： Raychaudhury B,Banerjee S,Gupta S,Singh RV,Datta SC

更新日期：2005-07-01 00:00:00

abstract：:The emergence of drug-resistance poses a major obstacle to the control of malaria. A homolog of the major multidrug-transporter in mammalian cells was identified, Plasmodium falciparum multidrug resistance protein-1, pfmdr1, also known as the P-glycoprotein homolog 1, Pgh-1. Several studies have demonstrated strong, a...

journal_title：Acta tropica

authors： Duraisingh MT,Cowman AF

更新日期：2005-06-01 00:00:00

abstract：:We evaluated the use of polymerase chain reaction (PCR) for diagnosis of mucosal leishmaniasis (ML) in an endemic area in Acre, Brazil, where Leishmania braziliensis is present. Leishmania DNA was detected 34 of 35 cases, yielding a positivity rate of 97.1%, which was higher than the positivity rates for all of the ot...

journal_title：Acta tropica

authors： Oliveira JG,Novais FO,de Oliveira CI,da Cruz Junior AC,Campos LF,da Rocha AV,Boaventura V,Noronha A,Costa JM,Barral A

更新日期：2005-04-01 00:00:00

abstract：:During an epidemic of cutaneous leishmaniais in northeast Brazil a prospective study was conducted in order to assess clinical, parasitological and immunological features of cutaneous leishmaniasis in a representative sample of patients. A general examination was done and demographic and anthropometric data as well as...

journal_title：Acta tropica

authors： Harms G,Fraga F,Batroff B,Oliveira F,Feldmeier H

更新日期：2005-03-01 00:00:00

abstract：:Studies on in vitro skin permeation and in vivo anti-leishmanial activity in mice experimentally infected with Leishmania (Leishmania) major pointed out to the potential of a new paromomycin (PA) formulation (hydrophilic gel) for treatment of cutaneous leishmaniasis (CL). In this study, the activity of this formulatio...

journal_title：Acta tropica

authors： Gonçalves GS,Fernandes AP,Souza RC,Cardoso JE,de Oliveira-Silva F,Maciel FC,Rabello A,Ferreira LA

更新日期：2005-02-01 00:00:00

abstract：:Two PCR methods were compared for their sensitivity in detecting cultured Leishmania major, before being used to estimate infection rates in female sandflies (Phlebotomus papatasi) collected from peridomestic animal shelters and the nearby burrows of the gerbil reservoir hosts, Rhombomys opimus, in Isfahan province, c...

journal_title：Acta tropica

authors： Parvizi P,Mauricio I,Aransay AM,Miles MA,Ready PD

更新日期：2005-01-01 00:00:00

abstract：:The structure of the Phlebotomine sand fly community from the Venezuelan Andes was studied using null-model tests. The analyses, at the living zones and altitudes scales, revealed C-scores larger than those expected by random, independently of the collection technique (P < 0.05). These results imply that sand fly spec...

journal_title：Acta tropica

authors： Chaves LF,Añez N

更新日期：2004-11-01 00:00:00

abstract：:The aim of this study was to assess, whether polymerase chain reaction (PCR) allows sensitive screening of treatment failure suspicions in areas, where drug resistance against African animal trypanosomosis (AAT) appears to be a problem. PCR was used to detect trypanosome infections prior to, 14 and 28 days after contr...

journal_title：Acta tropica

authors： Gall Y,Woitag T,Bauer B,Sidibe I,McDermott J,Mehlitz D,Clausen PH

更新日期：2004-09-01 00:00:00

abstract：:Equity is an important criterion in evaluating health system performance. Developing a framework for equitable and effective resource allocation for health depends upon knowledge of service providers and their location in relation to the population they should serve. The last available map of health service providers ...

journal_title：Acta tropica

authors： Noor AM,Gikandi PW,Hay SI,Muga RO,Snow RW

更新日期：2004-08-01 00:00:00

abstract：:A study of host preference in tsetse flies using a modified heteroduplex PCR-based method is described. Domestic and wild animal blood samples were collected to extract the corresponding reference DNAs. In Campo (south Cameroon), tsetse flies (mainly Glossina palpalis palpalis) were trapped and 41 bloodmeals were coll...

journal_title：Acta tropica

authors： Njiokou F,Simo G,Mbida Mbida A,Truc P,Cuny G,Herder S

更新日期：2004-07-01 00:00:00

abstract：:The cellular immune response in neurocysticercosis (NC) was studied in 22 patients, 11 (50%) of them in the inflammatory phase of the disease, by means of immunophenotyping of cells in cerebrospinal fluid (CSF) and peripheral blood (PB), lymphoproliferation assay with Taenia solium total saline extract (Tso) and Taeni...

journal_title：Acta tropica

authors： Bueno EC,dos Ramos Machado L,Livramento JA,Vaz AJ

更新日期：2004-07-01 00:00:00

abstract：:The process of invasion by apicomplexan parasites is a carefully coordinated process involving the regulated release of specialized secretory organelles. Several lines of evidence suggest that proteases are critical for the assembly and trafficking of organellar content proteins. Further, invasion is accompanied by cl...

journal_title：Acta tropica

authors： Kim K

更新日期：2004-06-01 00:00:00

abstract：:In Burkina Faso, where malaria is hyper-endemic and transmission intensity is very high, the majority of malaria-related morbidity and mortality occurs in children less than 5 years of age. A control measure such as the use of insecticide-treated curtains (ITC) significantly reduces transmission of malaria infection. ...

journal_title：Acta tropica

authors： Bolad A,Nebié I,Esposito F,Berzins K

更新日期：2004-05-01 00:00:00

abstract：:The population dynamics of the larval and adult life stages of the malaria vector Anopheles gambiae Giles were studied in Miwani, western Kenya, in relation to meteorological conditions. Larval density within a habitat, the number of larval habitats and sibling species composition were investigated as determinants of ...

journal_title：Acta tropica

authors： Koenraadt CJ,Githeko AK,Takken W

更新日期：2004-04-01 00:00:00

abstract：:An adaptation of a modified procedure using anion-exchange centrifugation was evaluated to isolate and freeze in field conditions a high number of bloodstream forms of Trypanosoma brucei gambiense for direct in vitro culture. Pellets of trypanosomes were obtained from 62 patients in Central Africa. The presence of try...

journal_title：Acta tropica

authors： Truc P,Likeufack CL,Mbongo N,Ebo'o Enyenga V

更新日期：2004-04-01 00:00:00